Application Type
Patent
Application SubType
PCT National Phase
(10) Registration Number and Date
BNN20190052 07.01.2020
Status
Registered
(180) Expiration Date
(20) Filing Number and Date
BN N/2019/0052 10.10.2017
(40) Publication Number and Date
BN N/2019/0052
A
07.01.2020
(86) PCT Filing Number and Date
(87) PCT Publication Number and Date
(85) National Entry Date
(30) Priority Details
US 62/554,817
06.09.2017
US 62/491,164
27.04.2017
US 62/406,252
10.10.2016
US 62/447,850
18.01.2017
US 62/566,093
29.09.2017
(51) IPC Classes
(71/73) Applicant
(72) Inventor
(74) Representative Name
(EN) AIP Law : Unit Nos. 404A-410A, 4th Floor, Wisma Jaya, Jalan Pemancha, Bandar Seri Begawan BS8811, Brunei Darussalam
(54) Title
(EN) SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
(57) Abstract
(EN)
Provided herein are compounds of the Formula I and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
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(58) Citations