Application Type
Patent
Application SubType
PCT National Phase
(10) Registration Number and Date
BNN20180102 10.12.2019
Status
Registered
(180) Expiration Date
(20) Filing Number and Date
BN N/2018/0102 05.05.2017
(40) Publication Number and Date
BN N/2018/0102
A
10.12.2019
(86) PCT Filing Number and Date
(87) PCT Publication Number and Date
(85) National Entry Date
(30) Priority Details
US 62/332,788
06.05.2016
(72) Inventor
(EN) DOBSON, Claire, Louise
(EN) SCHOFIELD, Darren
(EN) POLLIZZI, Kristen
(EN) MAZOR, Yariv
(EN) OBERST, Michael
(EN) HAMMOND, Scott, A.
(EN) LOBO, Brian
(EN) MANIKWAR, Prakash
(EN) SEAMAN, Jonathan
(EN) DOVEDI, Simon
(EN) CARLESSO, Gianluca
(74) Representative Name
(EN) Ahmad Isa & Partners : Unit Nos. 404A-410A 4th Floor, Wisma Jaya Jalan Pemancha Bandar Seri Begawan BS8811
(54) Title
(EN) BISPECIFIC BINDING PROTEINS AND USES THEREOF
(57) Abstract
(EN)

The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.

(58) Citations
Document Type Date Action
Event NameDateStatus
Filing05.05.2017Filed
PCT National Phase Entry05.11.2018PCT National Phase
Registration10.12.2019Registered
Publication10.12.2019Published