Application Type
Patent
Application SubType
PCT National Phase
(10) Registration Number and Date
BNN20190053 16.10.2021
Status
Registered
(180) Expiration Date
(20) Filing Number and Date
BN N/2019/0053 10.10.2017
(40) Publication Number and Date
BN N/2019/0053
A
16.10.2021
(86) PCT Filing Number and Date
(87) PCT Publication Number and Date
(85) National Entry Date
(30) Priority Details
US 62/531,690
12.07.2017
US 62/491,180
27.04.2017
US 62/406,275
10.10.2016
US 62/566,030
29.09.2017
US 62/447,849
18.01.2017
(51) IPC Classes
(71/73) Applicant
(72) Inventor
(EN) COLLIER, James : c/o Array BioPharma, Inc. 3200 Walnut St. Boulder, Colorado 80301
(EN) RAMANN, Ginelle A. : c/o Array BioPharma, Inc. 3200 Walnut St. Boulder, Colorado 80301
(EN) WALLS, Shane M. : c/o Array BioPharma, Inc. 3200 Walnut St. Boulder, Colorado 80301
(74) Representative Name
(EN) Spruson & Ferguson Pte Ltd : c/o Ahmad Isa & Partners Unit 404-A-410A 4th Floor,Wisma Jaya Jalan Pemancha Bandar Seri Begawan BS8811 Brunei Darussalam
(54) Title
(EN) SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
(57) Abstract
(EN) --
Provided herein are compounds of the Formula I: (I) or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
(58) Citations